Planetary bodies in our solar system may have locations that could harbor life, and such bodies are subject to major impact events. It is unclear to what extent life can survive these impacts and, if so, whether they can be transferred to other planetary bodies through impact ejecta (and potentially through returning spacecraft). During impact, lifeforms are subjected to high pressures and shear stresses. While the ability of prokaryotes to survive shock stress (used as a proxy for pressure) has been investigated, little is known about the effects of combined stress states (moving off the pressure axis) on the survivability of bacteria. To address this knowledge gap, we performed pressure-shear plate impact experiments on Deinococcus radiodurans, a polyextremophilic bacteria found in the Atacama Desert, a Mars analog environment, and known particularly for radiation resistance. Survival rate was determined by plating harvested cells and counting colony forming units (CFUs). Microscopy LIVE/DEAD assays were performed to capture counts of viable cells that may not form CFUs. The intent is to map a certain survival rate to a specific normal stress and shear stress as determined by impact velocity, material properties, and degree of tilt, and to assess the biological mechanisms that determine survival. These experiments will provide fundamental data relevant to astrobiology and planetary protection.