Three different boron carbide materials, with distinct microstructures, were impacted over two high velocity ranges to study their fracture mechanisms as well as crater formation and penetration performance. The first velocity range (1-3 km/s) was used to compare the materials without penetration, and the second velocity range (3-5 km/s) served to compare the penetration performance of these materials. Initial work by Malhotra and colleagues (ICACC 2022) had shown significant differences in the dominant failure mechanisms between the materials, as well as indications of improvement in penetration performance for one microstructure. This work seeks to improve and expand upon that work through more complete statistical investigations, as well as expanding the in-situ diagnostics during the tests. Post-mortem analysis of cratering and fracture surface through micro-CT and TEM are used to identify differences in failure mechanisms.